Work

Evidence-Based Medicine and the Problem of Healthy Volunteers

Year: 2017

Type: article

Abstract: Healthy controls are subjects without the disease being studied but may have other conditions indirectly affecting outcome. In the present epidemics of obesity a few subjects with undiagnosed nonalcoholic fatty liver disease enter clinical studies as controls, producing biased results. Stricter selection criteria should be considered to prevent this risk.

Source: Annals of Hepatology

DOI: 10.5604/01.3001.0010.5272

Authors: Giulio Marchesini, Francesca Marchignoli, Salvatore Petta

Institutions: University of Bologna, University of Palermo

Language: English

Topic: Liver Disease Diagnosis and Treatment

Subfield: Hepatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $1,500