Work

Optimization of a series of heterocycles as survival motor neuron gene transcription enhancers

Year: 2017

Type: article

Source: Bioorganic & Medicinal Chemistry Letters

DOI: 10.1016/j.bmcl.2017.10.066

Authors: Sungwoon Choi, Alyssa N. Calder, Eliza H. Miller, Kierstyn P. Anderson, Dawid K. Fiejtek, Anne Rietz, Hongxia Li, Jonathan J. Cherry, Kevin M. Quist, Xuechao Xing, Marcie A. Glicksman, Gregory D. Cuny, Christian L. Lorson, Elliot A. Androphy, Kevin J. Hodgetts

Institutions: Brigham and Women's Hospital, Harvard University, Indiana University School of Medicine, University of Missouri

Language: English

Topic: Neurogenetic and Muscular Disorders Research

Subfield: Genetics

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: FightSMA, Strong, National Institutes of Health, National Institute of Neurological Disorders and Stroke, Eunice Kennedy Shriver National Institute of Child Health and Human Development

Awards: Optimization of Compounds that Stabilize the SMN Protein for Treatment of SMA, Testing Compounds that Increase SMN levels for Efficacy in Mouse Models of SMA, Optimization of drug-like compounds for treatment of spinal muscular atrophy, Cooperative lead development program for treatment of spinal muscular atrophy

OpenAlex ID: W2765241324

FWCI: 0.314

Cites: 31

Cited by: 7

Related to: 10