Work

Intersubunit Crosstalk in the Rag GTPase Heterodimer Enables mTORC1 to Respond Rapidly to Amino Acid Availability

Year: 2017

Type: article

Source: Molecular Cell

DOI: 10.1016/j.molcel.2017.09.026

Authors: Kuang Shen, Abigail Choe, David M. Sabatini

Institutions: Broad Institute, Howard Hughes Medical Institute, Whitehead Institute for Biomedical Research, Koch Institute for Integrative Cancer Research At MIT, Massachusetts Institute of Technology

Language: English

Topic: PI3K/AKT/mTOR signaling in cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

Funders: U.S. Department of Defense, Life Sciences Research Foundation, National Institutes of Health, National Cancer Institute, National Institute of Allergy and Infectious Diseases

Awards: Regulation of the mTOR Pathway by Nutrients, Novel Components of the mTORC1 and mTORC2 Pathways, Cell Growth Signaling in Cancer Development, ROLE OF LYSOSOMAL TRANSPORTERS IN PROMOTING THE GROWTH OF CLEAR CELL RENAL CELL CARCINOMA AND OTHER TUMOR TYPES

OpenAlex ID: W2765487476

FWCI: 3.669

Cites: 49

Cited by: 100

Related to: 10