Work

Structure-activity relationships of 2-substituted phenyl-N-phenyl-2-oxoacetohydrazonoyl cyanides as novel antagonists of exchange proteins directly activated by cAMP (EPACs)

Year: 2017

Type: article

Source: Bioorganic & Medicinal Chemistry Letters

DOI: 10.1016/j.bmcl.2017.10.056

Authors: Zhiqing Liu, Yingmin Zhu, Haiying Chen, Pingyuan Wang, Fang C. Mei, Na Ye, Xiaodong Cheng, Jia Zhou

Institutions: The University of Texas Medical Branch at Galveston, The University of Texas Health Science Center at Houston

Language: English

Topic: Phosphodiesterase function and regulation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases

Awards: Exchange Protein directly Activated by cAMP (EPAC): Structure, Function and Therapeutics, Novel Pharmacological Probes Targeting Exchange Proteins Activated by cAMP (EPAC), Epac/cAMP-GEF, A Novel Intracellular cAMP Receptor, Preclinical Development of Novel Rickettsiosis Therapeutics Targeting EPAC1

OpenAlex ID: W2766588840

FWCI: 0.653

Cites: 31

Cited by: 12

Related to: 10