Endocrine Therapy for Early Breast Cancer: Updated Review.
Year: 2017
Type: review
Abstract: BACKGROUND: Although breast cancer is still the second most common cause of cancer-related deaths, breast cancer mortality has been declining because of advances in the use of adjuvant therapies. METHODS: We summarize clinical trials involving endocrine therapies used to treat early breast cancer and discuss their inception and recent advances. RESULTS: Endocrine therapies such as tamoxifen have revolutionized the treatment of breast cancer, resulting in significant decreases in cancer-related mortality. Aromatase inhibitors such as anastrozole and letrozole have further improved breast cancer survival. CONCLUSION: With the implementation of such therapies resulting in decreased mortality, patients with breast cancer are living longer than ever before. The focus of research is now directed toward the length of treatment and prediction models for recurrence.
Source: PubMed
Authors: Alexander Tremont, Jonathan Lu, John T Cole
Institutions: Ochsner Medical Center, The University of Queensland
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2766646724