Mngi-07. Red Blood Cell Transfusions Following Resection of Skull Base Meningiomas: Risk Factors and Clinical Outcomes
Year: 2017
Type: conference-abstract
Abstract: Red blood cell transfusion (RBCT) is used in a variety of capacities in neurosurgical practice, but risk factors for RBCT and clinical outcomes have not been described. To advance clinical understanding of blood transfusion in neurosurgery. We retrospectively reviewed adult patients who underwent resection of a meningioma at a single academic medical center and identified patients who had skull base meningiomas. Patients who were postoperatively transfused at least one unit of packed red blood cells (pRBCs) were compared to patients who were not transfused with pRBCs. One hundred and ninety-three patients underwent craniotomy for resection of a meningioma. Thirty-seven patients had non-recurrent skull base meningiomas. Seven of those patients received pRBCs after surgery. Skull base meningiomas were significantly associated with an increased risk of transfusion compared to non-skull base meningiomas (OR 3.89; 95% CI 1.34, 11.25). Meningioma size greater than 4.64 cm (OR 75; 95% CI 5.80, 970.66) and operative time greater than 10 hours (OR 16.25; 95% CI 2.32, 114.06) were significantly associated with an increased risk of transfusion. No adverse transfusion reactions were observed. Transfusion was associated with an increased risk of hospital stay greater than 14 days (OR 38.67; 95% CI 3.20, 467.74) and non-routine discharge (OR 11.30; 95% CI 1.37, 92.72). Skull base meningioma size greater than 4.64 cm and operative time greater than 10 hours were associated with an increased risk of RBCT but those effects did not appear to impact complication rate, hospital stay, or discharge disposition.
Source: Neuro-Oncology
Language: English
Subfield: Biochemistry
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2767804400