Work

In vitro activity of recombinant lysostaphin in combination with linezolid, vancomycin and oxacillin against methicillin-resistant Staphylococcus aureus.

Year: 2017

Type: article

Abstract: BACKGROUND AND OBJECTIVES: (MRSA) clinical isolates was determined. MATERIALS AND METHODS: synergistic activity of lysostaphin with linezolid, vancomycin and oxacillin, by checkerboard assay. RESULTS: Lysostaphin showed synergistic activity with linezolid and oxacillin, against all MRSA isolates, tested in the present study. Whereas, only 19.1% of the isolates showed synergistic activity with vancomycin and remaining 80.9% of the MRSA isolates showed additive activity. CONCLUSION: studies are warranted to confirm our results.

Source: Europe PMC (PubMed Central)

Authors: Nagalakshmi Narasimhaswamy, Indira Bairy, Gautham Shenoy, Laxminarayana Bairy

Institutions: Manipal Academy of Higher Education, Melaka Manipal Medical College, Ras al-Khaimah Medical and Health Sciences University

Language: English

Topic: Antimicrobial Resistance in Staphylococcus

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2768401666

FWCI: 1.06

Cites: 18

Cited by: 8

Related to: 10