Updating the MISEV minimal requirements for extracellular vesicle studies: building bridges to reproducibility
Year: 2017
Type: article
Abstract: An editorial describing “minimal experimental requirements for definition of extracellular vesicles (EVs)”, or\nmore simply “minimal information for studies of EVs (MISEV)” was published in the Journal of Extracellular\nVesicles in late 2014 [1]. Similar to guidelines in other scientific fields [2–4], “MISEV2014”, as we will call it\nhere, provided recommendations on experimental methods and minimal information in reporting. Specifically, three key areas were addressed: EV isolation/purification, EV characterization and EV functional studies (see Text Box 1).
Authors: Kenneth W. Witwer, Carolina Soekmadji, Andrew F. Hill, Marca H. Wauben, Edit I. Buzás, Dolores Di Vizio, Juan M. Falcon‐Perez, Chris Gardiner, Fred Hochberg, Igor V. Kurochkin, Jan Lötvall, Suresh Mathivanan, Rienk Nieuwland, Susmita Sahoo, Hidetoshi Tahara, Ana Claudia Torrecilhas, Alissa M. Weaver, Hang Yin, Lei Zheng, Yong Song Gho, Peter Quesenberry, Clotilde Théry
Institutions: Johns Hopkins University, Johns Hopkins Medicine, QIMR Berghofer Medical Research Institute, La Trobe University, Utrecht University, Semmelweis University, Hungarian Academy of Sciences, Cedars-Sinai Medical Center, Ikerbasque, CIC bioGUNE, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, University College London, University of California San Diego, Scintillon Institute, Sysmex (Japan), University of Gothenburg, Amsterdam UMC Location University of Amsterdam, Amsterdam University Medical Centers, University of Amsterdam, Icahn School of Medicine at Mount Sinai, Hiroshima University, Universidade Federal de São Paulo, Vanderbilt University, University of Colorado Boulder, Tsinghua University, Nanfang Hospital, Southern Medical University, Pohang University of Science and Technology, Brown University, Rhode Island Hospital, Inserm, Université Paris Sciences et Lettres, Institut Curie
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $4,410
Awards: G1040696225, G2157073800, G2344771908, UNDERSTANDING THE EXTRACELLULAR VESICLE-MEDIATED MECHANISM (S) OF RESISTANCE IN ADVANCED PROSTATE CANCER, Extracellular Vesicle-Mediated Immunomodulation in HIV Infection and Nicotine Abuse, G4119534169, G5850682332, Discovering novel players in mechanisms of extracellular vesicle release, cargo loading, and early pathogenesis of late-onset Alzheimer's Disease, G8773427133
OpenAlex ID: W2769100785