Work

Neuropathic Pain and Sleep: A Review

Year: 2017

Type: article

Abstract: Neuropathic pain is associated with sleep disturbances, and in turn poor sleep quality leads to increased pain sensitivity, so it is essential to assess sleep alongside neuropathic pain. Responses to drugs are inconsistent and identifying the best treatment option that will reduce pain and improve sleep quality remains challenging for clinicians. Anticonvulsants such as pregabalin and gabapentin improve neuropathic pain and have a positive effect on comorbid sleep disturbances. Opioids and antidepressants are effective in reducing pain but can exacerbate sleep disturbances. FUNDING: Pfizer, Italy.

Source: Pain and Therapy

DOI: 10.1007/s40122-017-0089-y

Author: Luigi Ferini-Strambi

Institutions: Vita-Salute San Raffaele University, IRCCS Ospedale San Raffaele

Language: English

Topic: Pain Mechanisms and Treatments

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $7,400