Work

GDC-0879, a BRAFV600E Inhibitor, Protects Kidney Podocytes from Death

Year: 2017

Type: article

Source: Cell chemical biology

DOI: 10.1016/j.chembiol.2017.11.006

Authors: Jonas Sieber, Nicolas Wieder, Abbe Clark, Manuel Reitberger, Sofia Matan, Jeannine Schoenfelder, Jianming Zhang, Anna Mandinova, Joshua Adam Bittker, Juan Gutierrez, Ozan Aygün, Namrata Udeshi, Steven Carr, Peter Mundel, Andreas Werner Jehle, Anna Greka

Institutions: Broad Institute, Brigham and Women's Hospital, Harvard University, Massachusetts General Hospital, Massachusetts Institute of Technology, University of Basel

Language: English

Topic: Renal Diseases and Glomerulopathies

Subfield: Nephrology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Science Foundation, Bristol-Myers Squibb, Brigham and Women's Hospital, Broad Institute, Deutsche Forschungsgemeinschaft, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases

Awards: G272491574, Role of podocyte cyclic AMP signaling in the progression of diabetic nephropathy, G3567343306, G3591663119, G4118778709, G5247860604, G5308430510, G544591541, Cell and molecular biological analysis of synaptopodin, Role of fatty acid metabolism for function and survival of podocytes, The role of Hic-5 in the regulation of podocyte motility, apoptosis and senescence and its relevance in progressive kidney diseases., G70167774, G7024155530, G9000037236, G9000100164, G9000192769, G9000196054, Molecular mechanisms of podocyte injury in FSGS

OpenAlex ID: W2771648208

FWCI: 1.978

Cites: 51

Cited by: 24

Related to: 10