Work

Oxidative cyclizations of oximes using hypervalent iodine reagents

Year: 2017

Type: article

Abstract: This account overviews oxidative cyclization reactions of aldoximes or ketoximes promoted by hypervalent iodine reagents.The oxidation of aldoximes by iodine(III) compounds generates nitrile oxides which can further react with appropriate substrates via intermolecular or intramolecular 1,3-dipolar cycloaddition reactions leading to a variety of nitrogen and oxygen heterocycles.Hypervalent iodine reagents can also react with ketoximes producing the corresponding heterocyclic products via intramolecular cyclization reactions.Recently, the oxidative cyclization reactions of aldoximes have been realized under catalytic conditions mediated by hypervalent iodine active species.

Source: ARKIVOC

DOI: 10.24820/ark.5550190.p010.013

Authors: Akira Yoshimura, Viktor V. Zhdankin

Institutions: Southern Methodist University, University of Minnesota, Duluth

Language: English

Topic: Oxidative Organic Chemistry Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

Funders: National Science Foundation, Division of Chemistry

OpenAlex ID: W2772831999

FWCI: 1.257

Cites: 75

Cited by: 18

Related to: 10