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Proteoform Suite: Software for Constructing, Quantifying, and Visualizing Proteoform Families

Year: 2017
Type: article
Abstract: We present an open-source, interactive program named Proteoform Suite that uses proteoform mass and intensity measurements from complex biological samples to identify and quantify proteoforms. It constructs families of proteoforms derived from the same gene, assesses proteoform function using gene ontology (GO) analysis, and enables visualization of quantified proteoform families and their changes. It is applied here to reveal systemic proteoform variations in the yeast response to salt stress.
DOI: 10.1021/acs.jproteome.7b00685
Authors: Anthony J. Cesnik, Michael R. Shortreed, Leah V. Schaffer, Rachel A. Knoener, Brian L. Frey, Mark Scalf, Stefan K. Solntsev, Yunxiang Dai, Audrey P. Gasch, Lloyd M. Smith
Language: English
Subfield: Spectroscopy
Field: Chemistry
Open Access status: green
OpenAlex ID: W2773340402
FWCI: 1.909
Cites: 35
Cited by: 45
Related to: 10