Aspergillus nosocomial infections Do cryptic species found in hospital environment matter
Year: 2016
Type: conference-paper
Abstract: Purpose - Aspergillus is a major threat causing nosocomial infections in immunocompromised patients, especially those subjected to transplantation. Until recently, species identification relief on morphological features. Advances in molecular methods allowed species identification through sequencing of specific genes, allowing high discrimination amongst isolates, which enables the genetic differentiation to species level of morphologically identical isolates. These are the so-called cryptic or sibling species. Different Aspergillus species have different susceptibilities to antifungals and several cryptic species have been described as less susceptible to specific antifungals. Therefore, we addressed the possible influence of hospital environmental isolates in the overall situation of Aspergillus antifungal resistance.
Authors: Raquel Sabino, Carla Viegas, Carla Veríssimo, M. Francisco, Christiane Martins, Karl V. Clemons, David A. Stevens
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2774019050