Work

Breaking the mold: structures of the RNA polymerase I transcription complex reveal a new path for initiation

Year: 2017

Type: editorial

Abstract: While structures of the RNA polymerase (Pol) II initiation complex have been resolved and extensively studied, the Pol I initiation complex remained elusive. Here, we review the recent structural analyses of the yeast Pol I transcription initiation complex that reveal several unique and unexpected Pol I-specific properties.

Source: Transcription

DOI: 10.1080/21541264.2017.1416268

Authors: Ashleigh J. Jackobel, Yan Han, Yuan He, Bruce A. Knutson

Institutions: SUNY Upstate Medical University, Northwestern University

Language: English

Topic: Genomics and Chromatin Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Funders: American Cancer Society, National Institutes of Health, National Cancer Institute

Awards: G13969156, Molecular mechanism of RNA polymerase I transcription and dysregulation in cancer

OpenAlex ID: W2776494466

Cites: 39

Cited by: 6

Related to: 10