Work

Investigating the Impact of Drug Crystallinity in Amorphous Tacrolimus Capsules on Pharmacokinetics and Bioequivalence Using Discriminatory In Vitro Dissolution Testing and Physiologically Based Pharmacokinetic Modeling and Simulation

Year: 2017

Type: article

Source: Journal of Pharmaceutical Sciences

DOI: 10.1016/j.xphs.2017.12.024

Authors: Hitesh S. Purohit, Niraj S. Trasi, Dajun D. Sun, Edwin C.Y. Chow, Hong Wen, Xinyuan Zhang, Yi Gao, Lynne S. Taylor

Institutions: Purdue University West Lafayette, United States Food and Drug Administration, Center for Drug Evaluation and Research, AbbVie (United States)

Language: English

Topic: Drug Solubulity and Delivery Systems

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funder: U.S. Food and Drug Administration

Award: G6162343052

OpenAlex ID: W2779386556

FWCI: 3.108

Cites: 49

Cited by: 70

Related to: 10