Year: 2018
Type: review
Abstract: Recent genome-wide association studies have catapulted the search for genes underlying human intelligence into a new era. Genome-wide polygenic scores promise to transform research on individual differences in intelligence, but not without societal and ethical implications, as the authors discuss in this Review. Intelligence — the ability to learn, reason and solve problems — is at the forefront of behavioural genetic research. Intelligence is highly heritable and predicts important educational, occupational and health outcomes better than any other trait. Recent genome-wide association studies have successfully identified inherited genome sequence differences that account for 20% of the 50% heritability of intelligence. These findings open new avenues for research into the causes and consequences of intelligence using genome-wide polygenic scores that aggregate the effects of thousands of genetic variants.
Source: Nature Reviews Genetics
DOI: 10.1038/nrg.2017.104
Authors: Robert Plomin, Sophie von Stumm
Language: English
Subfield: Experimental and Cognitive Psychology
Field: Psychology
Domain: Social Sciences
Open Access status: hybrid
Awards: G2496263360, G2761558319, G2973790809, G3207356259, G393177772, G4449678476, Aggression in Children: Unraveling gene-environment interplay to inform Treatment and InterventiON strateg, G4590952238, G463724992, Origins of learning difficulties and behaviour problems: from behavioural genetics to behavioural genomics., G4921234783, G536866722, G5702163051, Colorado Adoption Project/Twin Study of Lifespan behavioral development & cognitive aging [CATSLife2], Genetics of High Cognitive Abilities, G7624716486, G7716769900, G8658852833
OpenAlex ID: W2782281891