Work

Prediction of off-target activities for the end-to-end design of CRISPR guide RNAs

Year: 2018

Type: article

Source: Nature Biomedical Engineering

DOI: 10.1038/s41551-017-0178-6

Authors: Jennifer Listgarten, Michael Weinstein, Benjamin P. Kleinstiver, Alexander A. Sousa, J. Keith Joung, Jake Crawford, Kevin Gao, Luong Hoang, Melih Elibol, John G. Doench, Nicolo Fusi

Institutions: Microsoft (United States), Microsoft Research New England (United States), University of California, Los Angeles, Zymo Research Corporation (United States), Harvard University, Massachusetts General Hospital, Center for Computational and Integrative Biology, Massachusetts General Hospital, Broad Institute

Language: English

Topic: CRISPR and Genetic Engineering

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funder: National Cancer Institute

Award: Optimizing Cancer Immunotherapy Safety and Efficacy using Genome Editing

OpenAlex ID: W2782551527

FWCI: 9.99

Cites: 44

Cited by: 349

Related to: 10