Work

Could Dietary Glutamate be Contributing to the Symptoms of Obsessive-Compulsive Disorder?

Year: 2018
Type: article
Abstract: A 50-year-old man who had suffered from daily obsessive-compulsive disorder (OCD) symptoms for 39 years, in addition to fibromyalgia and irritable bowel syndrome symptoms, was enrolled in a randomized double-blind placebo-controlled clinical trial to test the effects of a low-glutamate diet on fibromyalgia/irritable bowel syndrome symptoms. After 1 month on the low-glutamate diet all of his symptoms remitted, including his OCD, which had previously been nonresponsive to pharmacological treatment. This case study is limited by self-report of symptoms; however, glutamatergic neurotransmission appears to be dysregulated in OCD, suggesting biological plausibility for this observation. Future research is needed.
Institution: American University
Language: English
Field: Psychology
Open Access status: gold
Estimated APC paid: $1,165
OpenAlex ID: W2783239167
FWCI: 0.553
Cites: 31
Cited by: 3
Related to: 10