Work

Dual gene activation and knockout screen reveals directional dependencies in genetic networks

Year: 2018

Type: article

Source: Nature Biotechnology

DOI: 10.1038/nbt.4062

Authors: Michael Boettcher, Ruilin Tian, James A Blau, Evan Markegard, Ryan T Wagner, David Wu, Xiulei Mo, Anne Biton, Noah Zaitlen, Haian Fu, Frank McCormick, Martin Kampmann, Michael T McManus

Institutions: University of California, San Francisco, Chan Zuckerberg Biohub San Francisco, UCSF Helen Diller Family Comprehensive Cancer Center, Emory University, Centre National de la Recherche Scientifique, Institut Pasteur

Language: English

Topic: CRISPR and Genetic Engineering

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: National Heart, Lung, and Blood Institute, National Institute of Mental Health, National Cancer Institute, National Institute of General Medical Sciences

Awards: Richer Models of Asthma Risk: Bridging the Environment-Genetics Divide, High Throughput Protein-Protein Interaction Interrogation in Cancer, Unlocking the Hidden Kinome, New Ways of Targeting K-Ras, Stress response networks in cancer: systematic mapping and therapeutic potential, Stress response networks in cancer: systematic mapping and therapeutic potential, Rewiring of the human protein homeostasis network in normal and disease contexts, Bay Area Cancer Target Discovery and Development Network

OpenAlex ID: W2783339841

FWCI: 7.204

Cites: 52

Cited by: 153

Related to: 10