Work

Human L- and M-opsins restore M-cone function in a mouse model for human blue cone monochromacy.

Year: 2018

Type: article

Abstract: Purpose: ) mouse model for BCM. Methods: eyes. Results: dorsal retina. Conclusions: mice, thus providing a proof-of-concept gene therapy in an animal model of BCM.

Source: PubMed Central

Authors: Wen-Tao Deng, Jie Li, Ping Zhu, Vince A Chiodo, W Clay Smith, Beau Freedman, Wolfgang Baehr, Jijing Pang, William W Hauswirth

Institutions: University of Florida, University of Utah

Language: English

Topic: Retinal Development and Disorders

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Eye Institute

Awards: Vision Research Core, Photoreceptor Ciliopathies: UNC119 Paralogs and NPHP10/NPHP5, Nikon A1R two-photon microscope for a shared resource, Membrane Protein Transport in Photoreceptors, Vision Research Training Grant at the University of Utah, University of Utah Core Vision Research Grant

OpenAlex ID: W2783409390

FWCI: 1.067

Cites: 44

Cited by: 29

Related to: 10