Work

The structural determinants of the bitopic binding mode of a negative allosteric modulator of the dopamine D 2 receptor

Year: 2018

Type: article

Source: Biochemical Pharmacology

DOI: 10.1016/j.bcp.2018.01.002

Authors: Christopher J. Draper-Joyce, Mayako Michino, Ravi Kumar Verma, Carmen Klein Herenbrink, Jeremy Shonberg, Anitha Kopinathan, Peter J. Scammells, Ben Capuano, David M. Thal, Jonathan A. Javitch, Arthur Christopoulos, Lei Shi, J. Robert Lane

Institutions: Monash University, National Institutes of Health, National Institute on Drug Abuse, New York State Psychiatric Institute, Columbia University

Language: English

Topic: Receptor Mechanisms and Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Health and Medical Research Council

Awards: Rational targeting of GPCRs towards treatment of schizophrenia, Understanding the major class of cell surface drug targets, G6969890512, G9000248939

OpenAlex ID: W2783787114

FWCI: 1.417

Cites: 42

Cited by: 32

Related to: 10