Year: 2018
Type: review
Abstract: This article reviews essential topics of canine visceral leishmaniasis (CVL) due to Leishmania infantum infection.It focuses on the current serological and molecular diagnostic methods used in epidemiological research and veterinary clinics to diagnose CVL and includes new point-of-care (POC) tests under development.The efficacy of different treatment regimens on the clinical improvement and infectiousness of dogs is also addressed.In the last section, the review provides a critical appraisal of the effectiveness of different control measures that have been implemented to curb disease transmission. Author summaryDogs are the principal reservoir hosts of L. infantum and consequently play a critical role in the transmission cycle of urban VL, which also affects humans.This review provides updated information on important topics such as diagnostic tests and dog treatments that improve dog health and decrease their transmission efficacy to insect vectors.A critical review of control measures is also provided.
Source: PLoS neglected tropical diseases
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,670
OpenAlex ID: W2783841473