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Understanding and addressing hepatitis C reinfection in the oral direct‐acting antiviral era

Year: 2018

Type: article

Abstract: The availability of effective, simple, well-tolerated oral direct-acting antiviral (DAA) hepatitis C regimens has raised optimism for hepatitis C virus (HCV) elimination at the population level. HCV reinfection in key populations such as people who inject drugs (PWID) and HIV-infected men who have sex with men (MSM) however threatens the achievement of this goal from a patient, provider and population perspective. The goal of this review was to synthesize our current understanding of estimated rates and factors associated with HCV reinfection. This review also proposes interventions to aid understanding of and reduce hepatitis C reinfection among PWID and HIV-infected MSM in the oral direct-acting antiviral era.

Source: Journal of Viral Hepatitis

DOI: 10.1111/jvh.12859

Authors: O. Falade‐Nwulia, M. S. Sulkowski, A. Merkow, C. Latkin, S. H. Mehta

Institution: Johns Hopkins University

Language: English

Topic: Hepatitis C virus research

Subfield: Hepatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute on Drug Abuse, National Institute of Allergy and Infectious Diseases