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Activation of the Anti-Aging and Cognition-Enhancing Gene Klotho by CRISPR-dCas9 Transcriptional Effector Complex

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Year: 2018
Type: article
Source: Journal of Molecular Neuroscience
DOI: 10.1007/s12031-017-1011-0
Authors: Ci-Di Chen, Ella Zeldich, Yuexuan Li, Andrea Yuste, Carmela R. Abraham
Institutions: Boston University, Klogene (United States)
Language: English

Topic: CRISPR and Genetic Engineering
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funders: Alzheimer's Drug Discovery Foundation, National Institutes of Health, National Institute on Aging
Awards: Alzheimer Disease Genetic Architecture in African Americans, G4122775913, G5010994669, Discovery of probes that enhance expression of the neuroprotective protein Klotho, Boston University Alzheimer's Disease Center, A NOVEL NEUROPROTECTIVE THERAPY FOR ALZHEIMER’S DISEASE
OpenAlex ID: W2784978409
FWCI: 2.134
Cites: 31
Cited by: 41
Related to: 10
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