Production of Trivalent Antigen-Specific T Cells Utilizing Viral Peptide Stimulation
Year: 2018
Type: article
Abstract: Virus-specific T cells (VSTs) have shown promising results in several clinical trials, utilizing effector cells that were isolated and expanded in one of three different ways. Our center has recently converted from utilizing transduced EBV transformed B cells to stimulate VSTs expansion to utilizing commercially-available peptide pools (PepMixes) for the stimulation.
Authors: Daria Heyenbruch, Angela Damen, Nan Gong, Katie Maurer, Michael S. Grimley, Adam S. Nelson, Stella M. Davies, Carolyn Lutzko, Xiang Zhu, Catherine M. Bollard, Patrick J. Hanley, Tom Leemhuis
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $3,650
OpenAlex ID: W2786071689