Work

Pharmacologic ascorbate (P-AscH−) suppresses hypoxia-inducible Factor-1α (HIF-1α) in pancreatic adenocarcinoma

Year: 2018

Type: article

Source: Clinical & Experimental Metastasis

DOI: 10.1007/s10585-018-9876-z

Authors: Justin G. Wilkes, Brianne R. O’Leary, Juan Du, Adrienne R. Klinger, Zita A. Sibenaller, Claire M. Doskey, Katherine N. Gibson-Corley, Matthew S. Alexander, Susan Tsai, Garry R. Buettner, Joseph J. Cullen

Institutions: University of Iowa, University of Iowa Holden Comprehensive Cancer Center, Medical College of Wisconsin, Veterans Health Administration, University of Iowa Hospitals and Clinics, Iowa City VA Medical Center, University of Iowa Health Care

Language: English

Topic: Cancer, Hypoxia, and Metabolism

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Veterans Affairs, National Institutes of Health, National Cancer Institute, National Institute of Environmental Health Sciences

Awards: G1089899480, University of Iowa Surgical Oncology Training Grant, Role of HIF-1 alpha in EcSOD-Induced Growth Inhibition of Pancreatic Cancer, The chemical biology of pharmacological ascorbate in cancer treatment, G6460835334, Pharmacological Ascorbate as a Radiosensitizer in Pancreatic Cancer, Training Program in Free Radical and Radiation Biology, Environmental Health Sciences Research Center, Cancer Center Support Grant

OpenAlex ID: W2786868231

FWCI: 1.36

Cites: 55

Cited by: 36

Related to: 10