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Multicenter Evaluation of Parametric Response Mapping (PRM) as an Indicator of Bronchiolitis Obliterans Syndrome after Hematopoietic Stem Cell Transplantation (HCT)

Year: 2018
Type: article
Study design: Observational Study
Abstract: Background: Parametric Response Mapping is a computed tomography (CT) based technology that classifies lung function based on a voxel-by-voxel comparison of lung attenuation changes from co-registered inspiratory and expiratory images (Figure 1). The utility of PRM as an imaging biomarker for identification of bronchiolitis obliterans syndrome (BOS) after HCT has previously been reported at a single center. The application of PRM technology to a larger cohort of patients with BOS, from additional centers and using different scan acquisition techniques is now examined.
DOI: 10.1016/j.bbmt.2017.12.607
Authors: Katherine Selwa, Craig J. Galban, Guang-Shing Cheng, Jonas Mattsson, Mats Remberger, Ben Himelhoch, Daniel McCaree, Margaret Guerriero, Timothy Hoffman, Joseph Brisson, Ryan Nazareno, Kiernan Bloye, Timothy D. Johnson, Ella A. Kazerooni, Gregory A. Yanik
Institutions: University of Michigan, Michigan Medicine, Fred Hutch Cancer Center, Karolinska University Hospital, Michigan State University, Seattle Cancer Care Alliance
Language: English
Subfield: Hematology
Field: Medicine
Open Access status: hybrid
Estimated APC paid: $3,650
OpenAlex ID: W2787055893
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