Genetic Associations with Day +100 Transplant Related Mortality (TRM) after HLA-Matched Unrelated Donor (MUD) Blood and Marrow Transplantation (DISCOVeRY-BMT Study)
Year: 2018
Type: article
Abstract: About 40% of patients die of various causes before 1-year post-MUD BMT with almost half of these deaths occurring in the first 100 days post-transplant. We performed a genome-wide association study (GWAS) of survival outcomes within 1 year in the DISCOVeRY-BMT study of patients treated for AML, MDS or ALL and reported to CIBMTR from 2000-2011 and their 8/8 HLA-MUD.
Authors: Abbas Rizvi, Ezgi Karaesmen, Leah Preus, Philip L. McCarthy, Marcelo C. Pasquini, Sachidanand Singh, Sandeep Kumar Singh, Kenan Onel, Xiaochun Zhu, Stephen R. Spellman, Christopher A. Haiman, Daniel O. Stram, Loreall Pooler, Xin Sheng, Qianqian Zhu, Li Yan, Qian Liu, Qiang Hu, Song Liu, Alyssa Clay-Gilmour, Sebastiano Battaglia, David Tritchler, Theresa E. Hahn, Lara Sucheston-Campbell
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,650
OpenAlex ID: W2787379961