Work

Urea and urine are a viable and cost-effective nitrogen source for Yarrowia lipolytica biomass and lipid accumulation

Year: 2018

Type: article

Source: Applied Microbiology and Biotechnology

DOI: 10.1007/s00253-018-8769-z

Authors: Matthew Brabender, Murtaza Shabbir Hussain, Gabriel Rodriguez, Mark A. Blenner

Institution: Clemson University

Language: English

Topic: Microbial Metabolic Engineering and Bioproduction

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Responsible consumption and production

Open Access status: closed

Funders: National Aeronautics and Space Administration, South Carolina Space Grant Consortium, Directorate for Engineering

Awards: G6218379124, SYNTHETIC BIOLOGY FOR RECYCLING HUMAN WASTE INTO NUTRACEUTICALS AND MATERIALS: CLOSING THE LOOP FOR LONG-TERM SPACE TRAVEL IT IS IMPRACTICAL FOR ASTRONAUTS TO TRAVEL WITH ALL NECESSARY SUPPLIES IN FUTURE LONG-TERM SPACE EXPLORATION MISSIONS. THEREFORE IT IS IMPERATIVE THAT TECHNOLOGIES ENABLING THE PRODUCTION OF FOOD NUTRACEUTICALS MEDICINE AND MATERIALS FROM EXTRATERRESTRIAL RESOURCES ARE DEVELOPED. THESE RESOURCES FOUND IN SPACE INCLUDE MINERALS AND FEEDSTOCKS FOUND ON DISTANT BODIES WASTE GENERATED BY HUMANS AND SPACE SHUTTLE OPERATION AND SOLAR ENERGY. TOGETHER WITH SYNTHETIC BIOLOGY-DRIVEN TECHNOLOGY FOR ENGINEERING MICROORGANISMS THAT CAN RELIABLY EFFICIENTLY AND FLEXIBLY UTILIZE SUCH "IN SITU RESOURCES" ASTRONAUTS WILL BE ABLE TO GENERATE THE FOOD NUTRACEUTICALS MEDICINE AND MATERIALS THEY NEED TO CARRY OUT THEIR MISSION. DUE TO POTENTIAL UNCERTAINTY IN RESOURCE AVAILABILITY THIS PROPOSAL FOCUSES ON ENGINEERING YEAST TO CONVERT RESPIRATION CO2 ALGAE BIOMASS AND HUMAN URINE INTO NUTRITIONAL OMEGA-3 FATS AND 3D PRINTABLE PLASTICS.

OpenAlex ID: W2787620644

FWCI: 1.135

Cites: 50

Cited by: 40

Related to: 10