Work

High Dose Chemotherapy Followed by Autologous Stem Cell Rescue for High Risk Soft Tissue Sarcoma: Retrospective Review

Year: 2018

Type: article

Abstract: Background: The role of high dose chemotherapy (HDC) and autologous stem cell transplantation in patients with high risk (advanced metastatic or relapsed) soft tissue sarcomas is controversial. Despite current advances in multimodal chemotherapy, radiotherapy, and local control measures, the prognosis of patients with advanced metastatic or unresectable and relapsed sarcomas remain poor with less than 10% 5 years disease free survival. Consolidation with HDC and autologous stem cell rescue (ASCR) may provide a benefit to a subgroup of high risk patients.

Source: Transplantation and Cellular Therapy

DOI: 10.1016/j.bbmt.2017.12.086

Authors: Sajad Khazal, Jonathan Gill, Richard Gorlick, Preethi Fernandez, Elodie Benard, Kris Michael Mahadeo

Institutions: The University of Texas MD Anderson Cancer Center, Albert Einstein College of Medicine, Children's Hospital at Montefiore

Language: English

Topic: Sarcoma Diagnosis and Treatment

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,650