Year: 2012
Type: dissertation
Study design: Observational Study
Abstract: Objective: To determine the prevalence of depression in pediatric patients with moderate to severe chronic kidney disease (CKD) and to identify associated patient characteristics.Methods: We performed a cross-sectional study to assess depression in patients aged 9-18 years with CKD stages III-V.Each patient completed the Child Depression Inventory-2 (CDI-2) and a parent completed the parent CDI-2.Criteria for the presence of depression were CDI-2 scores >64 or a prior diagnoses of depression currently being treated.Relative risks and 95% confidence intervals were calculated to determine the patient characteristics associated with depression.Results: Thirty-one percent of patients (13/42) met the criteria for depression, 18% of those ≤12 years and 35% of those >12 years.After adjusting for age and gender, risk of depression was relatively lower for patients with disease for ≤3 years (RR .19,95% CI: .03,1.23) and for those with CKD stage IV (RR .24,95% CI .06,1.02) and CKD stage V (RR .20,95% CI: .04,1.05) when compared to those with CKD stage III.In comparison to pre-end stage renal disease (ESRD) patients there was a lower risk for those on dialysis (RR .45,95% CI: .09,2.30) and a greater risk for those with a functioning transplant (RR 2.4, 95% CI: .98,5.9).Conclusion: There is a high prevalence of depression in pediatric patients with CKD.Patients with a functioning transplant or with CKD stage III may be at a relatively greater risk of depression.Our results are limited by statistical uncertainty due to the small sample size.
Author: Amy J. Kogon
Language: English
Subfield: Clinical Psychology
Field: Psychology
Domain: Social Sciences
Open Access status: green
OpenAlex ID: W2788164541