The consensus on indications, conditioning regimen, and donor selection of allogeneic hematopoietic cell transplantation for hematological diseases in China—recommendations from the Chinese Society of Hematology
Year: 2018
Type: article
Abstract: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is widely used to treat malignant hematological neoplasms and non-malignant hematological disorders. Approximately, 5000 allo-HSCT procedures are performed in China annually. Substantial progress has been made in haploidentical HSCT (HID-HSCT), pre-transplantation risk stratification, and donor selection in allo-HSCT, especially after the establishment of the "Beijing Protocol" HID-HSCT system. Transplant indications for selected subgroups in low-risk leukemia or severe aplastic anemia (SAA) differ from those in the Western world. These unique systems developed by Chinese doctors may inspire the refining of global clinical practice. We reviewed the efficacy of allo-HSCT practice from available Chinese studies on behalf of the HSCT workgroup of the Chinese Society of Hematology, Chinese Medical Association and compared these studies to the consensus or guideline outside China. We summarized the consensus on routine practices of all-HSCT in China and focused on the recommendations of indications, conditioning regimen, and donor selection.
Source: Journal of Hematology & Oncology
Institutions: Peking University People's Hospital, Academy of Military Medical Sciences, Shanghai Children's Medical Center, Chinese Academy of Medical Sciences & Peking Union Medical College, Institute of Hematology & Blood Diseases Hospital, First Affiliated Hospital Zhejiang University, Zhejiang University, First Affiliated Hospital of GuangXi Medical University, Chinese People's Liberation Army, Nanfang Hospital, Southern Medical University, Sichuan University, West China Hospital of Sichuan University, First Affiliated Hospital of Xinjiang Medical University, Peking University First Hospital, Henan Cancer Hospital, Anhui Provincial Hospital, Changhai Hospital, Peking Union Medical College Hospital, Wuhan Union Hospital, Huazhong University of Science and Technology, Center for Life Sciences
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $4,990
OpenAlex ID: W2789496953