Work

Gene Therapy for Color Blindness.

Year: 2017

Type: article

Abstract: mouse model using an rAAV.CBA.CNGA3 vector. We conclude by synthesizing the implications of this animal work for ongoing human trials, particularly, the challenge of restoring integrated cone retinofugal pathways in an adult visual system. The evidence to date suggests that gene therapy for achromatopsia will need to be applied early in childhood to be effective.

Source: PubMed Central

Authors: Mark M Hassall, Alun R Barnard, Robert E MacLaren

Institutions: University of Oxford, Oxford University Hospitals NHS Trust

Language: English

Topic: Retinal Development and Disorders

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2790065554

FWCI: 4.006

Cites: 46

Cited by: 38

Related to: 10