Year: 2018
Type: review
Abstract: The European Respiratory Society (ERS) Research Seminar entitled "Pulmonary vascular endothelium: orchestra conductor in respiratory diseases - highlights from basic research to therapy" brought together international experts in dysfunctional pulmonary endothelium, from basic science to translational medicine, to discuss several important aspects in acute and chronic lung diseases. This review will briefly sum up the different topics of discussion from this meeting which was held in Paris, France on October 27-28, 2016. It is important to consider that this paper does not address all aspects of endothelial dysfunction but focuses on specific themes such as: 1) the complex role of the pulmonary endothelium in orchestrating the host response in both health and disease (acute lung injury, chronic obstructive pulmonary disease, high-altitude pulmonary oedema and pulmonary hypertension); and 2) the potential value of dysfunctional pulmonary endothelium as a target for innovative therapies.
Source: European Respiratory Journal
Authors: Alice Huertas, Christophe Guignabert, Joan A. Barberà, Peter Bärtsch, Jahar Bhattacharya, Sunita Bhattacharya, Maria R. Bonsignore, Laurence Dewachter, Anh Tuan Dinh-Xuan, Peter Dorfmüller, Mark T. Gladwin, Marc Humbert, Tom Kotsimbos, Theodoros Vassilakopoulos, Olivier Sanchez, Laurent Savale, Ugo Testa, Martin R. Wilkins
Institutions: Université Paris-Sud, Inserm, Université Paris-Saclay, European Respiratory Society, Assistance Publique – Hôpitaux de Paris, Hypertension pulmonaire : physiopathologie et innovation thérapeutique, Hôpital Marie Lannelongue, Bicêtre Hospital, Centro de Investigación Biomédica en Red de Enfermedades Respiratorias, Consorci Institut D'Investigacions Biomediques August Pi I Sunyer, Universitat de Barcelona, University Hospital Heidelberg, Columbia University Irving Medical Center, Istituto di Biomedicina e di Immunologia Molecolare Alberto Monroy, National Research Council, University of Palermo, Université Libre de Bruxelles, Hôpital Cochin, Université Paris Descartes, University of Pittsburgh, Unité de recherche sur les maladies cardiovasculaires et métaboliques, Fondation pour l’innovation en Cadiométabolisme et Nutrition, Alfred Health, Monash University, National and Kapodistrian University of Athens, Hôpital Européen Georges-Pompidou, Institut Mondor de Recherche Biomédicale, Istituto Superiore di Sanità, Imperial College London
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2790265910