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Cryo-EM and X-ray structures of TRPV4 reveal insight into ion permeation and gating mechanisms

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Year: 2018
Type: article
Source: Nature Structural & Molecular Biology
DOI: 10.1038/s41594-018-0037-5
Authors: Zengqin Deng, Navid Paknejad, Grigory Maksaev, Monica Sala-Rabanal, Colin G. Nichols, Richard K. Hite, Peng Yuan
Institutions: Washington University in St. Louis, Memorial Sloan Kettering Cancer Center
Language: English

Topic: Ion Channels and Receptors
Subfield: Sensory Systems
Field: Neuroscience
Domain: Life Sciences

Open Access status: green

Funders: National Institutes of Health, National Heart, Lung, and Blood Institute, National Cancer Institute, National Institute of General Medical Sciences, National Institute of Neurological Disorders and Stroke, National Center for Research Resources
Awards: Pixel Array Detector for X-ray Crystallography, STRUCTURE AND MECHANISM OF A POLYMODAL TRP ION CHANNEL, Pixel Array Detector for Macromolecular Crystallography, Potassium Channels and Control of Cardiovascular Function, NE-CAT Center for Advanced Macromolecular Crystallography, Cancer Center Support Grant
OpenAlex ID: W2790336955
FWCI: 18.07
Cites: 87
Cited by: 214
Related to: 10
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