Long-Term Follow-Up of Adult Double Unit Cord Blood (CB) Transplantation (dCBT) Recipients Reveals High Rates of Progression-Free Survival after a Novel Cy/ Flu/ Thio/ TBI 400 Intermediate Intensity Conditioning Regimen
Year: 2018
Type: article
Abstract: Background: We have investigated CBT after a novel intermediate intensity, reduced toxicity myeloablative cyclophosphamide 50 mg/kg, fludarabine 150 mg/m2, thiotepa 5-10 mg/kg, 400 cGy TBI regimen with CSA/ MMF (no ATG) with an aim to reduce early organ toxicity while also maximizing engraftment & disease control.
Authors: Ioannis Politikos, Sean M. Devlin, Alexandra G. Jacob, Molly Maloy, Christopher Mazis, Kristine Naputo, Aishat Afuye, Andromachi Scaradavou, Richard J. O'Reilly, Scott T. Avecilla, Hugo Castro-Malaspina, Parastoo B. Dahi, Sergio A. Giralt, Boglarka Gyurkocza, Ann A. Jakubowski, Esperanza B. Papadopoulos, Jonathan U. Peled, Miguel-Angel Perales, Craig S. Sauter, Brian C. Shaffer, Gunjan L. Shah, Roni Tamari, Marcel R.M. van den Brink, James W. Young, Doris M. Ponce, Juliet N. Barker
Institution: Memorial Sloan Kettering Cancer Center
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,650
OpenAlex ID: W2790397953