Work

Biomarkers of aging associated with past treatments in breast cancer survivors: when therapy-induced pathways turn out to be potential therapeutic targets

Year: 2018

Type: article

Abstract: In a recent paper in NPJ Breast Cancer , Scuric et al. 1 found that in breast cancer patients, chemotherapy and radiation exposure were associated with some biomarkers of aging in white blood cell (WBC) and in peripheral blood mononuclear cells (PBMCs). Elevated levels of sTNF-RII, a biomarker of pro-inflammatory activation, were also detected. These results were obtained 3–6 years after the completion of primary treatments.

Source: npj Breast Cancer

DOI: 10.1038/s41523-018-0058-6

Authors: Wafaa Jabbour, Didier Wion

Institutions: Inserm, Brain Tech Laboratory, Université Grenoble Alpes

Language: English

Topic: Breast Cancer Treatment Studies

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,790