Perinuclear antineutrophil cytoplasmic antibody positive glomerulonephritis in a case of limited cutaneous scleroderma
Year: 2018
Type: article
Study design: Case Report
Abstract: Antineutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis in a patient of scleroderma is very rare. Very few cases have been reported in English literature. We report a case of a 58-year-old male with long-standing limited cutaneous scleroderma (Scl-70 positive) presenting with normotensive scleroderma renal crisis. Perinuclear ANCA with antimyeloperoxidase antibody was found to be strongly positive. Renal biopsy showed pauci immune-necrotizing crescentic glomerulonephritis. We believe that this case report will be helpful in understanding clinical features of normotensive ANCA-associated glomerulonephritis in scleroderma patients.
Source: Indian Journal of Nephrology
Authors: H Vora, B Kulkarni, S Singh, N Kulkarni
Institution: Kokilaben Dhirubhai Ambani Hospital
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W2790988121