Work

Perineural Invasion in Head and Neck Cancer

Year: 2018

Type: review

Abstract: Perineural invasion (PNI) is a mechanism of tumor dissemination that can provide a challenge to tumor eradication and that is correlated with poor survival. Squamous cell carcinoma, the most common type of head and neck cancer, has a high prevalence of PNI. This review provides an overview of clinical studies on the outcomes and factors associated with PNI in head and neck cancer and on findings on cancer-nerve crosstalk.

Source: Journal of Dental Research

DOI: 10.1177/0022034518756297

Authors: L.B. Schmitd, C.S. Scanlon, N.J. D’Silva

Institution: University of Michigan

Language: English

Topic: Head and Neck Cancer Studies

Subfield: Otorhinolaryngology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: University of Michigan, National Institutes of Health, National Institute of Dental and Craniofacial Research