Work

Will we be singing a different tune on combined post- and pre-capillary pulmonary hypertension?

Year: 2018

Type: article

Abstract: There have been many well-intended pursuits in medicine that should have panned out, but did not. Case in point: premature ventricular complexes (PVC) post-myocardial infarction were noted to be associated with increased risk of death, and thus the Cardiac Arrhythmia Suppression Trial (CAST) Study investigated if pharmacological PVC suppression with class I anti-arrhythmics would reduce the rate of arrhythmic death [1]. Surprisingly, the study showed that although PVCs were successfully suppressed, there were excess deaths due to arrhythmia and shock in such patients treated with encainide or flecainide [1]. More uncertainty in treating CpcPH with PAH specific therapy <http://ow.ly/W2XU30hMwGl>

Source: European Respiratory Journal

DOI: 10.1183/13993003.02589-2017

Authors: Steven Hsu, Ryan J. Tedford

Institutions: Johns Hopkins University, Medical University of South Carolina

Language: English

Topic: Pulmonary Hypertension Research and Treatments

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2792486458