Work

Outcomes after Second or Greater Hematopoietic Stem Cell Transplantation in Children with Inherited Metabolic Disorders

Year: 2018

Type: article

Abstract: Background: Inherited metabolic disorders (IMD) are a group of genetic disorders associated with significant morbidity and mortality. In select IMD, early intervention with hematopoietic stem cell transplant (HSCT) restricts disease progression and improves outcomes. However, due to a relatively high incidence of graft failure patients often undergo subsequent transplantation. There has been limited information about outcomes and risk factors for poor survival after subsequent HSCT. Analysis of these factors could help inform strategies for better outcomes in IMD patients.

Source: Transplantation and Cellular Therapy

DOI: 10.1016/j.bbmt.2017.12.507

Authors: Ashish Gupta, Troy C. Lund, Qing Cao, Paul J. Orchard, Weston P. Miller

Institution: University of Minnesota

Language: English

Topic: Hematopoietic Stem Cell Transplantation

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,650