Work

Phylogenetic Analysis of C Type Lectin from Toxocara canis Infective Larvae and Comparison with the C Type Lectin Family in the Immune System of Mouse and Human.

Year: 2018

Type: article

Abstract: BACKGROUND: CTL and other nematodes, and similar C type lectin involved in the immune system of mouse and human as their host. METHODS: infective larvae. The PCR amplification for C type lectin gene was performed and the amino acids were analyzed using the alignment method and the construction of phylogenetic tree. RESULTS: with mouse and human C type lectins. Its C type lectin showed a higher similarity with asialoglycoprotein receptor (ASGPR), macrophage lectin, dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN), MINCLE receptor of mouse and human. CONCLUSION: Analysis of CRD domain of C type lectin protein could make a better understanding of their role in the interaction of nematode parasite with their hosts.

Source: Europe PMC (PubMed Central)

Authors: Fazeleh Etebar, Seyed Hossein Hosseini, Fatemeh Jalousian, Mohammad Mehdi Ranjbar

Institutions: University of Tehran, Razi Vaccine and Serum Research Institute

Language: English

Topic: Helminth infection and control

Subfield: Parasitology

Field: Immunology and Microbiology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W2793292292

FWCI: 0.227

Cites: 21

Cited by: 6

Related to: 10