Work

Interfacing Cells with Vertical Nanoscale Devices: Applications and Characterization

Year: 2018

Type: review

Abstract: Measurements of the intracellular state of mammalian cells often require probes or molecules to breach the tightly regulated cell membrane. Mammalian cells have been shown to grow well on vertical nanoscale structures in vitro, going out of their way to reach and tightly wrap the structures. A great deal of research has taken advantage of this interaction to bring probes close to the interface or deliver molecules with increased efficiency or ease. In turn, techniques have been developed to characterize this interface. Here, we endeavor to survey this research with an emphasis on the interface as driven by cellular mechanisms.

Source: Annual Review of Analytical Chemistry

DOI: 10.1146/annurev-anchem-061417-125705

Authors: Allister F. McGuire, Francesca Santoro, Bianxiao Cui

Institutions: Stanford University, Italian Institute of Technology, Center for Advanced Biomaterials for Healthcare

Language: English

Topic: Cellular Mechanics and Interactions

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: National Science Foundation, National Institute of General Medical Sciences

Award: G5519393903