Work

Steroid-Refractory Graft Versus Host Disease (SR-GVHD) of the Gastrointestinal (GI) Tract is Frequently Associated with Transplant Associated Thrombotic Microangiopathy (TA-TMA)

Year: 2018

Type: article

Abstract: Background: SR-GVHD is a major cause of non-relapse mortality (NRM) associated with significant hospital stays and medical costs. TA-TMA is also a well-described cause of NRM resulting in multi-organ system failure. We sought to evaluate the incidence of TA-TMA in patients with severe GI GVHD and to assess risk factors for its development. We hypothesized that patients with SR-GVHD would require more transfusions, a surrogate for TA-TMA, than those without.

Source: Transplantation and Cellular Therapy

DOI: 10.1016/j.bbmt.2017.12.152

Authors: Sarah Wall, Qiuhong Zhao, Akwasi Agyeman, Steven M. Devine, Spero Cataland, Sumithira Vasu

Institution: The Ohio State University

Language: English

Topic: Hematopoietic Stem Cell Transplantation

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,650