A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein
Year: 2018
Type: article
Source: Nature Medicine
DOI: 10.1038/nm.4513
Authors: Joshua Tan, Brandon K Sack, David Oyen, Isabelle Zenklusen, Luca Piccoli, Sonia Barbieri, Mathilde Foglierini, Chiara Silacci Fregni, Jessica Marcandalli, Said Jongo, Salim Abdulla, Laurent Perez, Giampietro Corradin, Luca Varani, Federica Sallusto, Betty Kim Lee Sim, Stephen L Hoffman, Stefan H I Kappe, Claudia Daubenberger, Ian A Wilson, Antonio Lanzavecchia
Institutions: John Radcliffe Hospital, University of Oxford, Institute for Research in Biomedicine, Università della Svizzera italiana, Center for Infectious Disease Research, Scripps Research Institute, Swiss Tropical and Public Health Institute, University of Basel, SIB Swiss Institute of Bioinformatics, Ifakara Health Institute, University of Lausanne, ETH Zurich, Institute of Microbiology, Sanaria
Language: English
Topic: Malaria Research and Control
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funders: U.S. Department of Energy, Bill and Melinda Gates Foundation, Small Business Innovation Research, Deutsches Krebsforschungszentrum, Wellcome Trust, Tanzania Commission for Science and Technology, Helmut Horten Stiftung, Swiss Vaccine Research Institute, National Institutes of Health, Office of Science, National Institute of Allergy and Infectious Diseases, H2020 European Research Council
Awards: Mechanisms of antibody protection in pre-erythrocytic and blood stage malaria, G1286236842, Dissecting the antibody response to Plasmodium falciparum-infected erythrocytes, G2904193375, Plasmodium Falciparum Whole Sporozoite Malaria Vaccine, G3083819904, G3349051739, G382641700, G419881185, G42916606, G4501827968, G498139845, Structural, genetic and functional analyses of broadly neutralizing antibodies against human pathogens, G9000334340, G969889393
OpenAlex ID: W2793636839