RNA Biomarkers: Glycan Stimulation Enables Purification of Prostate Cancer Circulating Tumor Cells on PEDOT NanoVelcro Chips for RNA Biomarker Detection (Adv. Healthcare Mater. 3/2018)
Year: 2018
Type: article
Abstract: In article number 1700701, Hsiao-hua Yu and co-workers purified circulating tumor cells (CTCs) from blood samples of prostate cancer (PCa) patients. This platform not only captures CTCs with high efficiency and specificity, but also, released these cells gently by a competitive-binding mechanism. The purified CTCs provide well-preserved RNA transcripts for the analysis of the expression level of several PCa-specific RNA biomarkers, which could provide clinical insights into the disease and valuable information for cancer diagnosis and therapeutics.
Source: Advanced Healthcare Materials
Authors: Mo‐Yuan Shen, Jie‐Fu Chen, Chun‐Hao Luo, Sangjun Lee, Cheng‐Hsuan Li, Yung‐Ling Yang, Yu‐Han Tsai, Bo‐Cheng Ho, Li‐Rong Bao, Tien‐Jung Lee, Yu Jen Jan, Ya‐Zhen Zhu, Shirley Cheng, Felix Y. Feng, Peilin Chen, Shuang Hou, Vatche Agopian, Yu‐Sheng Hsiao, Hsian‐Rong Tseng, Edwin M. Posadas, Hsiao‐hua Yu
Institutions: Institute of Chemistry, Academia Sinica, Academia Sinica, Cedars-Sinai Medical Center, California NanoSystems Institute, University of California, Los Angeles, Ming Chi University of Technology, University of California, San Francisco, University of California San Francisco Medical Center, Research Center for Applied Science, Academia Sinica
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: bronze
OpenAlex ID: W2793669818