Work

Direct Regularization From Co-Registered Contrast MRI Improves Image Quality of MRI-Guided Near-Infrared Spectral Tomography of Breast Lesions

Year: 2018

Type: article

Abstract: An approach using direct regularization from co-registered dynamic contrast enhanced magnetic reson- ance images was used to reconstruct near-infrared spectral tomography patient images, which does not need image segmentation. 20 patients with mammography/ultrasound confirmed breast abnormalities were involved in this paper, and the resulting images indicated that tumor total hemoglobin concentration contrast differentiated malignant from benign cases (p-value = 0.021). The approach prod- uced reconstructed images, which significantly reduced surface artifacts near the source-detector locations (p-value = 4.16e-6).

Source: IEEE Transactions on Medical Imaging

DOI: 10.1109/tmi.2018.2794548

Authors: Limin Zhang, Shudong Jiang, Yan Zhao, Jinchao Feng, Brian W. Pogue, Keith D. Paulsen

Institutions: Dartmouth College, Tianjin University, Beijing University of Technology

Language: English

Topic: Optical Imaging and Spectroscopy Techniques

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Foundation for the National Institutes of Health, National Natural Science Foundation of China, National Cancer Institute, National Institute of Biomedical Imaging and Bioengineering