A Physiological Study to Determine the Enteral Threonine Requirements in Infants 1 to 6 Months of Age: Preliminary Results
Year: 2017
Type: dissertation
Abstract: Threonine is an indispensable amino acid that is greatly used by the gut and both deficient and excessive intakes of threonine are known to negatively impact the mucosal environment. Current infant threonine requirements are based on estimates of breast milk composition, however these estimates have not been validated using newer methods. The main objective of this thesis was therefore to determine the enteral threonine requirement in 1 to 6 month olds using the indicator amino acid oxidation method. Multiple methodological and ethical aspects were considered and provide the groundwork for the current and future enteral amino acid studies in infants. Thus far, preliminary results are encouraging and appear to demonstrate that study methods are working as anticipated. As enrolment ensues beyond the completion of this thesis, a threonine requirement for this 1 to 6 month old population will be defined.
Source: TSpace (University of Toronto)
Author: Veronik Connan
Language: English
Topic: Infant Nutrition and Health
Subfield: Nutrition and Dietetics
Field: Nursing
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2794289353