612: Pathologic Outcomes for Men on Active Surveillance who Undergo Radical Prostatectomy do not Differ from Men Undergoing Immediate Treatment
Year: 2007
Type: conference-abstract
Abstract: had clinically localized disease.Follow-up data showed that 88 (25%) patients had evidence of biochemical progression and 104 (30%) underwent additional treatments.A total of 125 (36%) patients progressed biochemically and/or underwent secondary treatments.Patients with biochemical progression were more likely to undergo additional treatment (p < 0.0001 ).Overall mortality was 30%, and Peaspecific mortality was 8%.No patient in the additional treatment group died of PCa versus 8 in the non-treatment group.A biopsy Gleason grade > 6 (16% vs 7 %, p = 0.02) and a clinical stage of T2 or greater (37% vs 27%, p = 0.005) were predictors of mortality from any cause.Continuing follow-up data are on this patient cohort will be presented.CONCLUSIONS: In men with screen-detected prostate cancer managed initially with watchful waiting, 36% of patients showed evidence of biochemical progression and/or underwent an alternative treatment.Some men developed metastatic disease and died of prostate cancer.
Source: The Journal of Urology
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2794497853