Work

Complexation of Chol-DsiRNA in place of Chol-siRNA greatly increases the duration of mRNA suppression by polyplexes of PLL(30)-PEG(5K) in primary murine syngeneic breast tumors after i.v. administration

Year: 2018

Type: article

Source: International Journal of Pharmaceutics

DOI: 10.1016/j.ijpharm.2018.03.045

Authors: Vishakha V. Ambardekar, Rajesh R. Wakaskar, Zhen Ye, Stephen M. Curran, Timothy R. McGuire, Don W. Coulter, Rakesh K. Singh, Joseph A. Vetro

Institutions: Lupin Pharmaceuticals (India), University of Nebraska Medical Center

Language: English

Topic: RNA Interference and Gene Delivery

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Cancer Institute, National Institute of General Medical Sciences, National Center for Research Resources, National Center for Advancing Translational Sciences

Awards: Nebraska Center for Nanomedicine, Nebraska Center for Nanomedicine, Development of Chol-DsiRNA Polyplexes to Improve the Therapy of Breast Cancer, Buffett Cancer Center Support Grant

OpenAlex ID: W2794602740

FWCI: 0.178

Cites: 19

Cited by: 6

Related to: 10